Biomedical Engineering Reference
In-Depth Information
L-cysteine
CdTe/ZnS QDs
TEOS
APTES
RAC
Rebinding template
Remove template
Figure 12.21
Schematic illustration showing the preparation of MIP-coated CdTe/ZnS
QDs [49].
(
a
)
E
xc
E
xc
hv
TNT
Quenching
hv
(
b
)
1
2
LUMO
HOMO
GQDs TNT
Resonance energy transfer
GQDs TNT
Charge transfer
Figure 12.22
(a) Schematic of the FRET-based GQDs sensor for detection of TNT. (b)
Quenching mechanism through (1) resonance energy transfer from the GQDs donor to
TNT acceptor, and (2) charge transfer from the excited GQDs to TNT (Reproduced with
permission from [50]).
acceptor through intermolecular polar-polar interactions at spatial prox-
imity. h e unmodii ed GQDs can sensitively detect down to 0.495 ppm
(2.2 mM) TNT with the use of only 1mL of GQDs solution. h e simple
FRET-based GQDs reported here exhibit high and stable l uorescence.
Eliminating further treatment or modii cation, this method simplii es and
shortens the experimental process.
