Biomedical Engineering Reference
In-Depth Information
-CDP
GO
-CDP/GO
Hydrazine
Hydrazine
-CDP/rGO
rGO
Guest molecule
Guest molecule
Figure 5.7
Schematic diagram of the procedure for preparing reduced-graphene
oxide (rGO) modii ed with water-soluble β-cyclodextrin polymer β-CDP. Adapted with
permission from [128].
others based on enzyme structures, because CD reduces signii cantly GR
aggregation and keeps an ef ective surface area, so the strong π-electrons
de-location can strongly interact with π electrons of MP. h is induces
superconductivity and a fast electron-transference resulting in an excel-
lent electrochemical response [41]. Generally, one of the most important
advantages of non-enzymatic sensors is the great stability on the response.
Table 5.3 shows some of the coni gurations based on GR and a compari-
son with other matrices reported, where ultrasensitive responses and low
detection limits can be observed.
In summary, we can conclude that progress on the development of new
biosensors for the quantitative detection of pesticides using nanomaterials
like GR has allowed the successful analysis of dif erent kinds of pesticides.
Biosensor's selectivity, response time and stability are closely related to the
selected enzyme, while the electrochemical response is largely associated
with the presence of GR. h e combination of both enzyme and nanoma-
terials in order to create nanobiomaterials has allowed very low detection
limits, making possible the detection of pesticides in real samples from
various sources such as water, soil, fruits and vegetables.
As expected, in the near future these substances will be detectable
in situ
and monitored in real time, allowing rapid decisions and actions for the
