Biomedical Engineering Reference
In-Depth Information
Table 5.2
Electrochemical strategies for phenol detection using GR based
biosensors.
Electrochemical
platform
Detection
technique
Sample
matrix
Analyte
L.O.D
Ref
HQ
CC
8.1 nM
26 nM
tap water, lake
wáter
GR-P4VP/GCE
DPV
98
BPA
CS/N-GS/GCE
5.0 nM
amperometry
river wáter
96
tap water
ground
water lake
water
graphene-gold
nanocomposite
i lm
HQ
RC
5.2 nM
2.2 nM
DPV
99
CC
phenol
BPA
0.23 nM
0.35 nM
0.72 nM
commercial
plastic
drinking
Gr-SP-Tyr/GCE
amperometry
97
HQ: hydroquinone; CC: catechol; RC: resorcinol; GR: Graphene; CTAB cetyltrimethyl-
ammonium bromide; GCE: glassy carbon electrode; CS: Chitosan; P4VP: poly (4-vinyl-
pyridine); SH :3-amino-5-mercapto-1,2,4-triazole; FEPA-CNP-GR: -4-ferrocenylethyne
phenylamine-carbon-graphene nanoparticles; N: Nai on; Tyr: tyrosinase.
are molded with PDMS generating a microl uidic channel, where the phe-
nol in injected (Figure 5.6). h e amperometric detection showed a detec-
tion limit of 50 nm, this value is related with the increment of the surface
area where the enzyme is immobilized besides the characteristic conduc-
tivity of GR [100].
Among the dif erent strategies to improve the quantii cation of phe-
nolic compounds like chlorophenols, carbon-paste electrode's modii ca-
tion with GR and β-cyclodextrin (β-CD) has been used (CD/GRs/CPE).
Quantii cation of 2-chlorophenol (2-CP) and 3-chlorophenol (3-CP) can
be easily achieve with detection limits of 0.2 y 0.09μM respectively. h is
sensor was successfully used in real water samples [101]. h e success of
this sensor is due to the presence of the β-CD because of its structure with
nanocavities, and because the supramolecular recognition of the specie,
which in combination with GR increases de surface area [102, 103].
