Biomedical Engineering Reference
In-Depth Information
TABLE 3.2
List of 44 Marketed Nano-Delivery Products
Product
Generic
Formulation
Indication
Manufacturer
Abraxane
Paclitaxel
Polymeric
nanoparticles
Cancer chemotherapy
Celgene
Abelcet
Amphotericin B
Liposomal
formulation
Fungal infections
Elan/Alkermes, Enzon,
Cephalon
Adagen
Adenosine deaminase
PEGylation
Enzyme replacement
therapy
Enzon, Sigma-Tau
AmBisome
Amphotericin B
Liposomal
formulation
Oral and perioral
infections
Astellas/Gilead Sciences
Amphotec
Amphotericin B
Liposomal
formulation
Oral and perioral
infections
Three Rivers
Pharmaceuticals/ALZA
Avinza
Morphine sulfate
Nanocrystal
formulation
Moderate-to-severe
pain
Elan/Alkermes, Pfizer
Copaxone
Glatiramer acetate
Copolymer of
l-glutamic acid,
l-alanine, l-tyrosine,
and l-lysine)
Multiple sclerosis
Teva Pharmaceuticals
Curosurf
Poractant alfa
Liposome
Neonatal respiratory
distress
Chiesi Farmaceutici SpA
DaunoXome
Daunorubicin
PEGylated liposome
formulation
Cancer chemotherapy
Gilead Sciences
DepoCyt
Cytarabine
Sustained-release
liposomes
Cancer chemotherapy
SkyePharma/Enzon
Depodur
Morphine sulfate
Liposome
Pacira Pharmaceuticals
Pacira Pharmaceuticals
Diprivan
Propofol
Liposomes
Induction of anesthesia
AstraZeneca
Doxil/Caelyx
Doxorubicin
PEGylated liposome
formulation
Cancer chemotherapy
ALZA/OrthoBiotech/
Schering Plough
Elestrin
Elestrin Estradiol gel
Phosphate
nanoparticles
Menopausal symptoms
BioSante
Elyzol
Metronidazole
Dental gel
Parodontitis Camurus
Camurus
Emend
Aprepitant
Nanocrystal
formulation
Antiemetic
Merck & Co+ Elan/
Alkermes
Epaxal
Hepatitis A vaccine
Virosome technology
Prevention of Hepatitis
A infection
Berna Biotech
Episil
Bioadhesive barrier
Fluidcrystal
Oral pain
Sinclair/Teva
Estrasorb
Estradiol gel
Micellar nanoparticles
Menopausal symptoms
Novavax/Espirit Pharma
Focalin XR
Dexmethylphen idate
hcl
Nanocrystals
ADHD
Novartis Élan/Alkermes
Fosrenol
Lanthanum carbonate
Inorganic
nanoparticles
End-stage renal
disease
Shire
Genexal PM
Paclitaxel
Polymeric micelles
Cancers
Samyang
Indaflex
Indomethacin
Solid/lipid
nanoparticles
Osteoarthritis
AlphaRx
Inflexal V
Subunit influenza
vaccine
Virosome
Influenza prophylaxis
Crucell
Invega
Sustenna
Paliperidone
Nanocrystal
Antipsychotic
Janssen
Macugen
Pegaptanib
Pegylated anti-VEGF
aptamer
Age-related macular
degeneration
OSI Pharmaceuticals/
Pfizer
continued
