Biomedical Engineering Reference
In-Depth Information
organism, in response to a perturbation (Rusyn and Daston, 2010). In addition, the information from
toxicogenomics can also be used to identify pathways, which are responsible for the toxic proper-
ties. Combined with the conventional methods of toxicity studies, toxicogenomics has the potential
to reveal the underlying mechanisms of nanotoxicity and establish a system to predict nanotoxic-
ity for both government and industry. To date, there are many predictive models for conventional
chemicals, which are convenient, fast, and relatively reliable, but not specific for nanomaterials.
These models, with certain adjustments, may be evolved to be applicable for nanoparticles.
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