Chemistry Reference
In-Depth Information
The other one D -ribose is found in ribonucleic acids (RNA) :
The sugars are in the furanose form. They are linked through the hydroxyl groups on carbons 3 and
5 as phosphate esters. The heterocyclic amine “bases” are attached at carbon 1, replacing the hydroxyl
group.
A sugar molecule with a base attached to it is referred to as a nucleoside :
NH 2
N
N
N
N
O
OH
OH
A nucleoside esterified with phosphoric acid is called a nucleotide :
NH 2
N
N
N
N
O
O
HO
P
OH 2 C
OH
OH OH
All the heterocyclic amines that occur in nucleic acids (DNA and RNA) are derivatives of either
pyrimidine or purine. These are:
NH 2
NH 2
O
H
CH 3
CH 3
N
N
N
N
N
N
O
O
O
H
H
H
cutosine
5-methylcytosine
thymine
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