Risk Assessment of Manufactured Nanomaterials - Environmental and Human Health Impacts of Nanotechnology - page 403

Physicochem Data Health Hazard Date Environmental Hazard/Fate Data Safety Hazard

Data

Exposure Data

Technical and commer-
cial name

Short term toxicity 28 day inhalation study Acute aquatic toxicity

Fish

Flammability Manufacture

Common form (90 day observation period) Invertebrates

Aquatic plants

Explosivity Processing

Chemical composition
(including surface
coating)

Single dose instillation study (90 day
observation period) 28 day repeated dose
oral study (90 day observation period)

Terrestrial toxicity
Invertebrates
Plants

Incompatibility Use

Molecular and crystal
structure

Physicochemical properties
(including list)
Adsorption-desorption coeffi cients

Reactivity Distribution/

storage

Physical form/shape (at
room temperature and
pressure)

Aggregation or disaggregation in
media

Particle size, size distribu-
tion and surface area

Skin sensitisation/irritation Corrosivity Environmental

releases

Particle density Skin penetration Persistence potential screen Post-use

management

Solubility (in water and
biologically relevant
fl uids)

Genetic toxicity tests Biodegradability (organic based)

Photodegradability/photo
transformation
Stability in water
Bioaccumulation

Dispersability Additional Data Additional Data Additional Data

Bulk density Biological fate and behaviour ADME on aquatic organisms Stability

Agglomeration state Chronic inhalation/ingestion Chronic toxicity (aquatic, terres-

trial, microorganisms)

decomposition

Porosity Chronic dermal irritation/sensitisation Additional species Polymerisation

Surface charge Developmental and reproductive Avian toxicity testing Photoactivity

Surface reactivity Neurotoxicity Population/ecosystem-level studies

Extensive genotoxicity studies Activated sludge respiration-

inhibition test

Focused toxicity studies (susceptibility
studies; allergencity and immunotoxicity
organ-function bioassays)

Microorganism toxicity
Persistence potential
Transformations via oxidation/
reduction reactions Endocrine disruption studies