Transgenic Vegetables - Transgenic Horticultural Crops: Challenges and Opportunities - page 38

TABLE 2.1 (continued)
Vegetable Crop Species That Have Been Engineered to Express Speciic Transgenes, and their Resulting Effects

Crop Traits Gene Expressed Result References

Vaccine/
medical

Human.interleukin-12.(IL12) Reduced.bacterial.load.when.fed.to.mice.infected.with.

mycobacteria

[79]

Modiied.human.alpha-1-antitrypsin Accumulation.of.high.levels.of.biologically.active,.therapeutic.

protein

[130]

Human.beta-amyloid Accumulation.of.high.levels.of.the.protein,.when.fed.to.mice.

exhibited.an.immune.response

[131]

HIV-1.Tat.protein,.fruit-speciic.expression High.levels.of.protein.accumulation,.that.produced.an.

immune.response.in.mice.when.consumed

[65]

Hepatitis.B.virus.large.surface.antigen,.fruit-speciic.
expression

High.levels.of.protein.accumulation.in.mature.fruits [66]

Human.coagulation.Factor.IX,.fruit-speciic.
expression

High.levels.of.functional.protein [81]

Hepatitis.B.surface.antigen Immune-primed.mice.when.fruit.was.orally.consumed [67]

Partial.ORF2.of.Hepatitis.E.virus Produced.immunoactive.Hepatitis.E.protein [68]

Insect.
resistance

Potato.polyphenol.oxidase
Bacillus thuringiensis .Cry6A

Increased.resistance.to.common.cutworms
Increased.resistance.to.root.knot.nematode

[2]
[16]

Poplar.chitinase,.leaf.expression Delayed.development.of.Colorado.potato.beetle.larvae [3]

Potato.PI-II.and.carboxypeptidase.inhibitors,.
proteinase.inhibitors,.leaf-speciic.expression

Increased.resistance.to. Heliothis obsoleta .and. Liriomyza
trifolii .larvae

[5]

Note: . Gene.expression.was.constitutive.unless.otherwise.stated.