Biomedical Engineering Reference
In-Depth Information
(a) Calculate the oxygen concentration in the arterial blood leaving the
oxygenator.
(b) How many membrane units are required [8]?
2.39
The lung capillary pressure varies between 2 to 12 mmHg and the lung inter-
stitial pressure varies from
7 to 1 mmHg. The plasma oncotic pressure var-
ies from 20 to 35 mmHg and interstitial oncotic pressure varies from 5 to 18
mmHg. If two liters per day of water is transferred, what is the coefficient of
filtration when (a) the reflection coefficient is 1 and (b) the reflection coeffi-
cient is 0.9?
−
2.40
In Example 2.11, if 1% (by wt) albumin is used instead of glucose, what is the
change in the solvent transfer? For albumin, the reflection coefficient is 0.9.
References
[1]
Hines, A. L., and R. N. Maddox,
Mass Transfer Fundamentals and Applications,
Upper
Saddle River, NJ: Prentice-Hall, 1985.
[2]
Collins, M. C., and W. F. Ramirez, “Mass Transport Through Polymetric Membranes,”
J.
Phys. Chem.,
Vol. 83, 1979, pp. 2294-2301.
[3]
Thorne, R. G., S. Hrabetova, and C. Nicholson, “Diffusion of Epidermal Growth Factor in
Rat Brain Extracellular Space Measured by Integrated Optical Imaging,”
J. Neurophysiol.,
Vol. 92, No. 6, 2004, pp. 3471-3481.
[4]
Stroh, M., et al., “Diffusion of Nerve Growth Factor in Rat Striatum as Determined by
Multiphoton Microscopy,”
Biophys. J.,
Vol. 85, No. 1, July 2003, pp. 581-588.
[5]
Falk, B., S. Garramone, and S. Shivkumar, “Diffusion Coeffi cient of Paracetamol in a Chi-
tosin Hydrogel,”
Materials Letter,
Vol. 58, No. 26, 2004, pp. 3261-3265.
[6]
Wissing, H., “Pharmacokinetics of Inhaled Anaesthetics in a Clinical Setting: Comparison
of Desfl urane, Isofl urane and Sevofl urane,”
British Journal of Anaesthesia,
Vol. 84, No. 4,
2000, pp. 443-449.
[7]
Floate, S., and C. E. W. Hahn, “Electrochemical Reduction of the Anaesthetic Agent Sevo-
fl urane (Fluromethyl 2,2,2-Trifl uoro-1-[Trifl uoromethyl] Ethyl Ether) in the Presence of
Oxygen and Nitrous Oxide,”
Sensors and Actuators B, Chemical,
Vol. 99, No. 2-3, 2004,
pp. 236-252.
[8]
Ethier, C. R., and C. A. Simmons,
Introduction to Biomechanics: From Cells to Organisms,
Cambridge, U.K.: Cambridge University Press, 2007.
Selected Bibliography
Amidon, G. L., et al., “Quantitative Approaches to Delineate Passive Transport Mechanisms in
Cell Culture Monolayers,”
Transport Processes in Pharmaceutical Systems,
2000, pp. 219-316.
Bird, R. B., E. N. Lightfoot, and W. E. Stewart,
Transport Phenomena,
2nd ed., New York: John
Wiley & Sons, 2006.
Chung, S. H., O. S. Andersen, and V. Krishnamurthy, (eds.),
Biological Membrane Ion Channels:
Dynamics, Structure, and Applications,
New York: Springer, 2006.
Crank, J.,
The Mathematics of Diffusion,
2nd ed., Oxford, U.K.: Clarendon Press, 1979.
Deen, W. M.,
Analysis of Transport Phenomena,
Oxford, U.K.: Oxford University Press, 1998.
Fournier, R. L.,
Basic Transport Phenomena in Biomedical Engineering,
2nd ed., London, U.K.:
Taylor and Francis, 2006.
