Monitoring Neurological Injury by qEEG - Quantitative EEG Analysis Methods and Clinical Applications - page 185

80

60

40

20

Conventional TH

0 Immediate TH

2 hours after TH 24 hours 48 hours 72 hours

(a)

80

60

40

20

Conventional TH

0 Immediate TH

2 hours after TH 24 hours 48 hours 72 hours

(b)

Figure 7.10 NDS score by hypothermia and injury groups, Median (25th to 75th percentile): best

outcome 0. TH: therapeutic hypothermia. A significant difference was noted

over the 72-hour experiment in (a) 7-minute immediate hypothermia (7IH) versus conventional
hypothermia (7CH) ( p = 0.001) and (b) 9-minute IH (9IH) versus CH (9CH) ( p = 0.022) asphyxial CA.
Significant differences existed in all periods between the 7-minute groups and at 2 hour
posthypothermia between the 9-minute groups (* p < 0.05, ** p < 0.01). Note that qEEG was able to
detect the significant difference as early as 30 minutes between the 9-minute groups, and qEEG val-
ues correlated well with 72-hour NDS values as early as 1 hour after CA. ( From: [62]. © 2008 Elsevier.
Reprinted with permission.)

80; worst outcome

= =