Agriculture Reference
In-Depth Information
Chapter 1
N
ITROFURANS IN
P
OULTRY
:
U
SE
,
C
ONTROL
AND
R
ESIDUE
A
NALYSIS
Jorge Barbosa
1
, Simone Ferreira
2
, Alberto Canelas
Pais
2
, Maria Irene Noronha da Silveira
3
and
Fernando Ramos
3
1
INRB-LNIV, Laboratório Nacional de Investigação Veterinária,
Estrada de Benfica, 701, 1549-011 Lisboa - Portugal
2
Department of Chemistry, University of Coimbra, Rua Larga,
3004-535 Coimbra, Portugal
3
CEF - Center for Pharmaceutical Studies, Health Sciences Campus,
Pharmacy Faculty, Coimbra University, Azinhaga de Santa Comba,
3000-548 Coimbra, Portugal
A
BSTRACT
The administration of pharmacologically active substances to poultry
should not originate the presence of residues of the referred substances or
their metabolites in foods for human consumption. As such, the EU has
been introducing certain restrictions in the use of some groups of
veterinary drugs and the prohibition of others. Furazolidone, furaltadone,
nitrofurazone and nifursol are nitrofuran antibiotics used in poultry,
cattle, pigs and fish. These compounds are used for prophylactic and
therapeutical treatments of infections caused by a large number of
bacteria, including Gram positive (
Staphylococcus, Streptococcus,
Clostridium
and many
Corynebacterium
), Gram negative (
Escherichia
