Biomedical Engineering Reference
In-Depth Information
Oxytocin cells
0.08
Real cell
Model cell
0.12
0.06
0.08
0.04
0.04
0.02
0
0
0.12
0.04
0.08
0.02
0.04
0
0
0.1
0.3
0.5
0
0.1
0.2
Vasopressin in cells
0.06
0.06
0.04
0.04
0.02
0.02
0
0
0.06
0.06
0.04
0.04
0.02
0.02
0
0
0.1
0.3
0.5
0.04
0.14
0.24
Interval (s)
Figure 7.3
Left panels: inter-spike interval distributions from two oxytocin cells (top) and two
vasopressin cells (bottom), each of which is modelled by a modified leaky-integrate-
and-fire model neuron (see text). The histograms from the model cells are super-
imposed on the original cell data. Right panels: hazard functions plotted from the
same data for each cell and each model neuron superimposed. The interspike inter-
val distributions of oxytocin cells and vasopressin cells can be fit remarkably well
with relatively simple models, that in the case of oxytocin cells mimic the effects of a
HAP only, and for vasopressin cells that mimic the effects of a HAP and subsequent
DAP.
Search WWH ::
Custom Search