Chemistry Reference
In-Depth Information
AMIDES
O
C NH
2
R
Manufacture:
+ N H
3
CH
3
COOH
CH
3
CONH
2
+ H
2
O
acetamide
CH
3
COCl +
NH
+
HC l
CH CONH
3
3
2
CH
3
CO
O
+NH
3
CH
3
CONH
2
+
CH
3
COOH
CH
3
CO
+ NH
3
CH
3
COOC
2
H
5
CH
3
CONH
2
+ C
2
H
5
OH
NH
2
, the compound
produced is an
amide
. Amides are neutral to mildly basic compounds. They
can be made from acids, acid chlorides, acid anhydrides, and esters by
reaction with ammonia or primary and secondary amines. The amide linkage
is found in polyamide resins such as nylon.
Urea, NH
2
CONH
2
, is the diamide of carbonic acid, (HO)
2
CO, and is
manufactured in large volume for use in fertilizers and plastics by the reaction
of carbon dioxide and ammonia.
When the
−
OH of a carboxylic acid is replaced by an
−
