Biomedical Engineering Reference
In-Depth Information
Fig. 2.
Involvement of
I
f
in pacemaking: hyperpolarization triggers electrical activity. Application
of hyperpolarizing steps to a depolarized SAN cell shows activation of
I
f
starting at -40 mV.
Electrical activity becomes more stable and persistent at more negative voltages. Reprinted from
Ref. 16, with permission.