Biomedical Engineering Reference
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Fig. 3. Pacemaker current I f in embryonic murine ventricle. Panel a action potentials at stage
9.5 days post coitum ( dpc ). Panel b action potentials at stage 18 dpc. Panel c activation of I f
upon hyperpolarizing pulses at 9.5 dpc. Panel d activation of I f upon hyperpolarizing pulses at
18 dpc. Right panel Expression of HCN1 mRNA, HCN2 mRNA and HCN4 mRNA at 9.5 and
18 dpc. Compiled from [66].
Fig. 4. Action potentials of a single sinus node cell isolated from a rabbit sinus node. There is
no beat-to-beat regularity. Horizontal bar 100 ms. Vertical bar 50 mV. Reproduced with
permission from [43].
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