Biomedical Engineering Reference
In-Depth Information
Fig. 1. a
The degree of Cx-40 expression in neuregulin-1 treated cells and in the control group,
evaluated by optical densitometry. Neuregulin-1 Į has a significant positive impact on Cx-40
expression.
b
The degree of Cx-40 expression in cAMP treated cells and in the control group,
evaluated by optical densitometry. cAMP has a significant positive impact on Cx-40
expression.
Table 1.
Expression levels of connexins as identified by mean fluorescence intensity (MFI) of
Į-actinin positive cardiomyocytes after immunostaining and analysis by flowcytometry
Mean MFI
SD
N
P
Connexin 40
Control
29.4
8.8
5
NS
Camp
34.3
3.0
5
Neuregulin
a
32.3
9.9
3
Connexin 43
Control
61.3
9.6
3
NS
Camp
80.5
11.7
4
Neuregulin
a
57.6
9.0
3
Connexin 45
Control
537.7
84.7
3
NS
Camp
649.5
123.3
4
564.5 71.4 2
There was no significant impact of neuregulin or cAMP on the
expression of Cx-40, Cx-43 and Cx-45
Neuregulin
a
