Biomedical Engineering Reference
In-Depth Information
biomedicine. JSim downloads are available for the Windows, Macintosh, and Linux
platforms from the National Simulation Resource at the University of Washington
(http://nsr.bioeng.washington.edu/). Another example is the 'CellML' language,
Table 4. Cardiac cell models available on the Internet
Source code
Source code of numerous models in CellML format [31, 49]
Web address: http://www.cellml.org/models/
Source code of cardiac cell models from the Rudy group (C++,
MATLAB)
Web address: http://www.rudylab.wustl.edu/
Source code of cardiac cell models from the Winslow group
(C++, Fortran)
Web address: http://www.ccbm.jhu.edu/
Source code of the 'Kyoto model' [55, 75] (several formats)
Web address: http://www.card.med.kyoto-u.ac.jp/simulation/
C++ source code of the Bernus et al. human ventricular cell
model [2]
Web address: http://www.physiol.med.uu.nl/wilders/
C++ source code of the ten Tusscher et al. human ventricular cell
models [80, 81]
Web address: http://www-binf.bio.uu.nl/khwjtuss/
Fortran source code of the Zhang et al. rabbit sinoatrial cell
models [93, 94]
Web address: http://www.personalpages.manchester.ac.uk/staff/
H.Zhang-3/
Ready-to-use Java applets
Java applets of numerous ionic models [22]
Web address: http://www.arrhythmia.hofstra.edu/
iCell: Java-based interactive cell modelling resource [10]
Web address: http://www.ssd1.bme.memphis.edu/icell/
simBio: Java package for 'biological dynamic simulation' [76]
Web address: http://www.sim-bio.org/
Ready-to-use Windows programs
COR (cellular open resource): comes with various ionic models
[27]
Web address: http://www.cor.physiol.ox.ac.uk/
LabHEART: Windows version of Puglisi-Bers rabbit ventricular
cell model [71]
Web address: http://www.meddean.luc.edu/templates/ssom/
depts/physio/labheart.cfm
See Table 1 of Ref. [76] for a comprehensive list of tools for
cardiac cell modelling
which is an open standard based on the XML markup language, being developed by the
Bioengineering Institute at the University of Auckland and affiliated research groups
[31, 49]. The purpose of CellML is to provide a means for unambiguous specification of
biological models, which can be used to store and exchange such models. The structure
of a CellML document is such that it can both be used to generate equations suitable for
publishing and to generate a computer code to perform simulations, thus ensuring that
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