Chemistry Reference
In-Depth Information
Figure 3.4 Relationship between the equilibrium association constant (K
eq
) and the rate
constants for supramolecular association and dissociation.
whether controlled by the SP equilibrium structure or reversible kinetics, are slowed
by both mechanisms.
The independent control of the association kinetics relative to thermodynamics is
therefore desirable, and Yount and others showed that N,C,N-pincer metal-ligand
coordination motifs such as 1
.
2 (Fig. 3.5) are well suited to that goal. Pincer com-
pounds 1 and analogs have been synthesized and studied extensively (Rietveld
et al. 1997; Albrecht and van Koten 2001; Rodriguez et al. 2002; Slagt et al.
Figure 3.5 Pincer-ligand motifs that provide independent control of supramolecular asso-
ciation/dissociation kinetics relative to thermodynamics.
