Chemistry Reference
In-Depth Information
Figure 15.11 Sensor response to herbicide concentration obtained with a polymer imprinted
with atrazine. Reprinted from Sergeyeva et al. (1999). Copyright 1999 Elsevier Science.
Fig. 15.11). The sensor has response times of 6-15 min, depending on the membrane
thickness, and the polymer membranes maintained their recognition characteristics
over 6 months.
15.6. CONCLUSIONS AND OUTLOOK
The use of MIPs as artificial recognition elements for the chemical sensor is practical
and promising. MIPs can be easily synthesized for sensing molecules when biologi-
cal receptors can not be easily obtained. Their low cost, ease of preparation, and
robustness, coupled with the wide choice of templates and functional monomers
make MIPs appropriate for the recognition element in sensing applications. Great
efforts have been made to develop the combination of MIPs and transducing
devices over the past two decades.
The development of MIPs with a more homogeneous distribution of binding sites,
which also possess high affinity to the target molecule and good selectivity in
aqueous environments, will attract broad interest for developing MIP-based chemical
sensors. Then, MIP-based chemical sensors will find great opportunities in the areas
where other natural or synthetic receptors struggle to find reliable applications.
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Albert KJ, Lewis NS, Schauer CL, Sotzing GA, Stitzel SE, Vaid TP, Walt DR. Cross-reactive
chemical sensor arrays. Chem Rev 2000;100:2595-2626.
Alexander C, Andersson HS, Andersson LI, Ansell RJ, Kirsch N, Nicholls IA, O'Mahony J,
Whitcombe MJ. Molecular imprinting science and technology: a survey of the literature for
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