Chemistry Reference
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Figure 11.22 (a) Cholesteryl-oligo(
L
-lactic acid)-(lysine) G2 amphiphiles and (b) variations
in aggregate morphology with dendron generation.
deformation even upon drying, they were capable of reversibly encapsulating
porphyrin. More recently, dendritic-helical diblock copolypeptides composed of a
hydrophobic poly(g-benzyl-
L
-glutamate) block terminated with a hydrophilic
poly(
L
-lysine) dendron were similarly observed to aggregate into micelles whose
morphologies changed with the generation following Israelachvilli's predictions
(Fig. 11.25; Kim et al. 2006).
Accordingly, the morphology of the micellar assemblies transitioned from large
objects with low curvature at a low dendron generation to smaller vesicular/spherical
structures with high curvature at higher generations.
