Crystallization of Proteins: Principles and Methods - Molecules: Nucleation, Aggregation and Crystallization - page 126

Any of the methods discussed above can be used to grow macromol-
ecular crystals. Keeping an open mind is essential as no single method is
superior to another.
Acknowledgments
The author would like to acknowledge Prof. Naomi Chayen for a critical
reading of the manuscript and valuable discussions, and Dr. Sahir
Khurshid for providing some of the figures. The author would like to
thank Barnali and Bhaskar for their invaluable help in the illustration of
the phase diagram. The UK Engineering and Physical Sciences Research
Council (EPSRC) and the European Commission OptiCryst Project (SHG-
CT-623-2006-037793) are acknowledged for financial support.
References
Anderson MJ, Hansen CL, Quake SR. (2006) Phase knowledge enables
rational screens for protein crystallization. Proc Nat Acad Sci USA
103 : 16746-16751.
Asherie N. (2004) Protein crystallization and phase diagrams. Methods
34 : 266-272.
Ataka M, Tanaka S. (1986) The growth of large single-crystals of
lysozyme. Biopolymers 25 : 337-350.
Chayen NE. (2005) Protein Crystallization — The current challenge. Euro
Pharma Rev 3 : 106-111.
Ducruix A, Giege R. (1999) Crystallization of Nucleic Acids and Proteins:
A Practical Approach , 2nd Edn. Oxford University Press, Oxford.
Feher G, Kam Z. (1985) Nucleation and growth of protein crystals:
General principles and assays. Methods Enzymol 114 : 77-112.
Garcia-Ruiz JM, Gonzalez-Ramirez LA, Gavira JA, Otalora F. (2002)
Granada Crystallization Box: A new device for protein crystallization
by counter-diffusion techniques. Acta Crystallogr D 58 : 1638-1642.
Haas C, Drenth J. (1999) Understanding protein crystallization on the
basis of the phase diagram. J Cryst Growth 196 : 388-394.