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Fig. 10.3   Internalization of mesoporous silica nanoparticle [MSN] by plant cell. Type I: Fluores-
cein-labeled MSN; Type II: Type I MSN coated with Triethylene Glycol (TEG) polymer; Type
III: Fluorescein-labeled MSN capped by gold nanoparticles; Type IV: β-estradiol-loaded MSN
with gold nanoparticle capping. After action of the gene gun, MSNs [small circles], carrying the
small effector molecule (β-estradiol) within the gold-capped structure and externally coated with
plasmid DNA, penetrate the cell wall and, in some cases, enter the cytoplasm. The MSNs are
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