Biomedical Engineering Reference
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incorporated the global shape information into segmentation by using an elliptic
Fourier decomposition of the boundary and placing a Gaussian prior on the Fourier
coefficient. Chan et al. [35] and Leventon et al. [29] introduced the shape priors
into geodesic active models. To improve the robustness of level set-based methods
to noisy and incomplete data, Rousson and Paragios combined a shape influence
term [36].
3. LEVEL SET METHODS AND IMAGE SEGMENTATION
3.1. Formulations
The level set method, developed by Osher and Sethian, is a zero equivalent
surface method [18]. Its basic idea is to change the movement track of a planar
curve into the movement track of a three-dimensional surface. Though this conver-
sion complicates the solution, it exhibits many other advantages: parameter-free
representation, topological flexibility, and the ability to handle local deformations
are its main strengths. These properties make the level set framework a suitable
choice for describing cardiac structure.
The classical level set boundary is defined as a zero level set of an implicit
representation Φ of the evolving curve. In detail, we now evolve the implicit
level set function Φ( x, y, t ), to denote the evolution of a curve Γ( t ) in its normal
direction with a speed F ( x, y ). At time t , the zero level set ( x, y ) |
φ ( x, y, t )=0
describes the evolved contour Γ( t ), namely,
Φ(Γ( t ) ,t )=0 .
(1)
When we differentiate this equation with respect to t and use the chain rule, we
have
∂φ
∂t +
∂t
·
φ
.
(2)
Because F denotes the speed of the curve in its normal direction, it can be char-
acterized as
∂t ·
N = F,
(3)
where N represents the outwards normal, and can be obtained by
φ
N =
.
(4)
|∇
φ
|
Substitute Eqs. (3) and (4) into (2), and we can get the evolution equation for φ as
Φ t + F
|∇ Φ | =0 .
(5)
 
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