Biomedical Engineering Reference
In-Depth Information
Table 3 Some examples of the involvement of developmental signaling pathways in cancer
stem cells
Pathway
Tumor
Stem cell
Authors
Wnt
Colorectal cancer
Intestinal
epithelial
stem cells
Korinek et al. (1998), van de Wetering
et al. (2002)
Lymphoblastic
leukemia
Hematopoietic
stem cells
Willert et al. (2003), Reya et al. (2003),
Chung et al. (2002), Qiang et al. (2003)
Medulloblastoma
Cerebellar
granule cell
progenitors
Zurawel et al. (1998), Cui et al. (1998)
Shh
Glioma
Neural stem
cells
Lai et al. (2003), Ruiz i Altaba et al.
(2002)
Medulloblastoma
Cerebellar
granule cell
progenitors
Wechsler-Reya and Scott (1999), Raffel
et al. (1997), Pietsch et al. (1997),
Goodrich et al. (1997)
Notch
Lymphoblastic
leukemia
Hematopoietic
stem cells
Pear et al. (1996), Varnum-Finney et al.
(2000)
Breast cancer
Mammary
epithelial
stem cells
Chepko and Dickson (2003), Jhappan
et al. (1992)
Acknowledgment Supported by the Kazan Foundation and, the NIH/NCI R011R01CA093
708-01A3 grant and the NIH/NCI 1R01CA132566-01 grants. We would also like to thank
Dr. Genevie` ve Cle´ ment for helping with proof reading.
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