Biomedical Engineering Reference
In-Depth Information
BrdU:
bromodeoxyuridine,
SP:
side populations,
ABC:
ATP-binding cassette,
ABCG2:
ABC transporter subfamily member 2,
wnt:
wingless-type MMTV site family,
LRP5/6:
low density lipoprotein receptor-related protein 5/6,
GSK-3b:
glycogen synthase kinase 3-beta,
TCF:
T-cell transcription factor,
LEF:
lymphoid enhancer-binding factor,
EMT:
epithelial-to-mesenchymal transition,
WIF1:
wnt inhibitory factor 1,
SFRP:
secreted frizzled-related protein,
DKK:
Dickkopf,
IHh:
Indian hedgehog,
DHh:
desert hedgehog,
SHh:
sonic hedgehog,
PTCH:
patched,
Gli:
glioma-associated oncogene homolog,
SMOH:
smoothened,
FRZ:
frizzled,
HIP:
hedgehog-interacting protein,
Fu:
fused,
SuFu:
suppressor of fused,
ARF:
INK4A/ADP ribosylation factor,
ADAM:
a disintegrin and metalloproteinase, S; synthesis,
Oct:
octamer-binding transcription factor,
Sox:
SRY-box 2,
DAPT:
N-[N-(3,5-difluorophenacetyl)-
L
-alanyl]-S-phenylglycine t-
butyl ester,
VEGF:
vascular endothelial growth factor,
TGFb:
transforming growth factor beta
Acknowledgments This publication has been funded in part with Federal funds from the National
Cancer Institute, National Institutes of Health, under contract No. N01-CO-12400. This research
was supported in part by the Intramural Research Program of the NIH, National Cancer Institute.
References
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Prospective identification of tumorigenic breast cancer cells. Proc. Natl Acad. Sci. USA
100:3983-3988.
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