Chemistry Reference
In-Depth Information
TABLE 7.1 HMGS containing biosynthetic pathways and their producing organisms
Producing
Discrete
KS
ECH
1
ECH
2
Natural product
organism
ACP
(Cys
→
Ser)
HMGS
(Dehydration)
(Decarboxylation)
Bacillaene
Bacillus subtilis
168
/B.
amyloiquefaciens
AcpK/ BaeF
PksF
PksG/ BaeG
PksH/ BaeH
Pksl/Bael
Bryostatin
Candidatus
Endobugula
sertula
BryQ
BryR
Curacin
Lyngbya majuscula
CurB
CurC
CurD
CurE
CurF N-terminal domain
Difficidin
Bacillus
amyloiquefaciens
DifC
DifN
DifO
Jamaicamide
Lyngbya majuscula
JHB
JamF
JamG
JamH
JamI
JamJ N-terminal domain
Leinamycin
Streptomyces
atroolivaceus
LnmL
LnmM
LnmF
Mupirocin
Pseudomonas fluorescens
Macp14
MupG
MupH
MupJ
MupK
Myxovirescin A
(antibiotic TA)
Myxococcus xanthus
DK1622
TaB & TaE
TaK
TaC & TaF
TaX
TaY
Onnamide
Symbiont bacterium of
Theonella swinhoei
OnnA
OnnB (embedded)
Pederin
Symbiont bacterium of
Paederus fuscipes
PedN
PedM
PedP
PedL
PedI (embedded)
Virginiamycin M
Streptomyces virginiae
VirB
VirC
VirD
VirE
