Chemistry Reference
In-Depth Information
FBDD
fragment-based drug discovery
FID
free induction decay
FPMSMA
(4-fluorophenyl)methylsulfanylmethanimidamide
GPCR
G-protein coupled receptor
IMAC
immobilized metal affinity chromatography
LPC
lysophosphatidylcholine
NTA
nitrilotriacetic acid
PBS
phosphate-buffered saline
PEEK
polyether ether ketones
QSAR
quantitative structure-activity relationship
SCA
scaffold-based classification approach
SDS
sodium dodecyl sulfate
SPR
surface plasmon resonance
STD
saturation transfer difference
TINS
target-immobilized NMR screening
TMA
tetramethylammonium chloride
TSP
trimethylsilyl-2,2,3,3-tetradeuteropropionic acid
References
[1] Murali, N., Miller, W. M., John, B. K., Avizonis, D. A. and Smallcombe, S. H. (2006)
J. Magn.
Reson.
179
, 182-189.
[2] Hajduk, P. J. and Greer, J. (2007)
Nat. Rev. Drug Discov.
6
, 211-219.
[3] Lipinski, C. A., Lombardo, F., Dominy, B. W. and Feeney, P. J. (1997)
Adv. Drug Deliv. Rev.
23
, 3-25.
[4] Overington, J. P., Al Lazikani, B. and Hopkins, A. L. (2006)
Nat. Rev. Drug Discov.
5
, 993-996.
[5] Vanwetswinkel, S., Heetebrij, R. J., van Duynhoven, J., Hollander, J. G., Filippov, D. V., Hajduk,
P. J. and Siegal, G. (2005)
Chem. Biol.
12
, 207-216.
[6] Marquardsen, T., Hofmann, M., Hollander, J. G., Loch, C. M. P., Kiihne, S. R., Engelke, F. and
Siegal, G. (2006)
J. Magn. Reson.
182
, 55-65.
[7] Minic, J., Grosclaude, J., Aioun, J., Persuy, M. A., Gorojankina, T., Salesse, R., Pajot-Augy, E.,
Hou, Y. X., Helali, S., Jaffrezic-Renault, N., Bessueille, F., Errachid, A., Gomila, G., Ruiz, O.
and Samitier, J. (2005)
Biochim. Biophys. Acta Gen. Subj
.
1724
, 324-332.
[8] Siegal, G., AB, E. and Schultz, J. (2007)
Drug Discov. Today
12
, 1032-1039.
[9] Congreve, M., Carr, R., Murray, C. and Jhoti, H. (2003)
Drug Discov. Today
8
, 876-877.
[10] Babaoglu, K. and Shoichet, B. K. (2006)
Nat. Chem. Biol.
2
, 720-723.
[11] Lepre, C. A. (2001)
Drug Discov. Today
6
, 133-140.
[12] Baurin, N., Aboul-Ela, F., Barril, X., Davis, B., Drysdale, M., Dymock, B., Finch, H.,
Fromont, C., Richardson, C., Simmonite, H. and Hubbard, R. E. (2004)
J. Chem. Inf. Comput.
Sci
44
, 2157-2166.
[13] Jacoby, E., Davies, J. and Blommers, M. J. J. (2003)
Curr. Top. Med. Chem.
3
, 11-23.
[14] Carney, S. (2007)
Drug Discov. Today
12
, 789-793.
[15] Xu, J. (2002)
J. Med. Chem.
45
, 5311-5320.
[16] Hajduk, P. J., Huth, J. R. and Fesik, S. W. (2005)
J. Med. Chem.
48
, 2518-2525.
[17] Klein, J., Meinecke, R., Mayer, M. and Meyer, B. (1999)
J. Am. Chem. Soc.
121
, 5336-5337.
[18] Nordin, H., Jungnelius, M., Karlsson, R. and Karlsson, O. P. (2005)
Anal. Biochem
.
340
,
359-368.