Information Technology Reference
In-Depth Information
0123456789012345678901234567890
*b+a-aQab+//+b+
babbabbbababbaaa
(2.5)
It codes for the following ET:
b
a
a
Q
a
Note that in this case the ORF ends at position 7, whereas the gene ends at
position 30 and, therefore, a noncoding region of 23 elements, apparently
doing nothing, exists downstream of the termination point.
Suppose now a mutation occurred in the coding region of the gene, spe-
cifically at position 6, changing the “Q” into “*”. Then the following gene is
obtained:
0123456789012345678901234567890
*b+a-a
*
ab+//+b+
babbabbbababbaaa
(2.6)
And its expression gives:
b
a
a
a
b
In this case, the termination point shifts just one position to the right (position
8), with the new expression tree managing to keep most of the characteristics
of the original one.
Consider another mutation in chromosome (2.5) above, the substitution of
“a” at position 5 by “+”. In this case, the following daughter chromosome is
obtained:
