Biomedical Engineering Reference
In-Depth Information
Fig. 20.2.
Tissue microarray construction and automated TMA construction:
TMAs are constructed by identifying the site of interest on the donor recipient block
(a)
, placing the biopsy into the recipient block in an organized way
(b)
, and section-
ing the block using the tape transfer method
(c)
(Instrumedics Inc., New Jersey).
This process can be automated as in the prototype model displayed in which multi-
ple blocks can be simultaneously biopsed and cores inserted into multiple recipient
TMA blocks, under computer control