Chemistry Reference
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therapeutic compounds. The study and evaluation of carbohydrate- carbohydrate
interactions go hand in hand with the development of novel and more sensitive
experimental approaches to better understand the nature and biological roles of
these low - affi nity interactions that govern essential cellular processes.
Summary Box
Carbohydrate-carbohydrate interactions provide a highly versatile mechanism
based on the low affi nity and polyvalent confi guration of carbohydrate chains.
Carbohydrates offer many combinatorial possibilities for fi nely tuned cellular
adhesion and recognition processes, as well as for interactions between drugs
or natural ligands with DNA. Precision and sensitivity of novel experimental
approaches allow more thorough investigation of these interactions at the
single - molecule level.
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