Chemistry Reference
In-Depth Information
Type IVb pili
PilA
Vibrio cholera
Mannose
Intestine
Antibiotic - associated diarrhea
Enteropathogenic
Escherichia coli
N
- Acetyllactosamine
Epithelial cells in the intes-
tine
Diarrhea
Surface lectins
BabA
Helicobacter pylori
L e
b
, H type 1, ALe
b
Stomach epithelial cells
Peptic ulcer disease, MALT lympho-
ma or gastric cancer
SabA
Helicobacter pylori
SLe
x
Stomach epithelial cells and
progenitor cells
Peptic ulcer disease, MALT lympho-
ma or gastric cancer
LecA (PA - IL)
Pseudomonas
aeruginosa
Gal
α
1,4Gal (in P1, p
k
),
Epithelial cells
Infects patients with cystic fi brosis,
pneumonia, cancer or injured cor-
neas
Gal
1,3Gal (in blood group
B antigen)
α
Fucose, Le
a
, Le
x
LecB (PA - IIL)
Pseudomonas
aeruginosa
Epithelial cells
Infects patients with cystic fi brosis,
pneumonia, cancer or injured cor-
neas
Toxins
Toxin A
Clostridium diffi cile
Gal
α
1,3Gal
β
1,4GlcNAc,
Epithelial cells in the intes-
tine
Antibiotic - associated diarrhea
(Le
x
, Le
y
)
C T
Vibrio cholerae
GM1
Polarized intestinal epithelial
cells
Diarrhea
H T
Escherichia coli
GM1, GM2, paragloboside
Intestinal epithelial cells
Diarrhea
S T
Escherichia coli
Intestinal epithelial cells
Diarrhea
α
1,2 - Fucosylated structures
Shiga toxin
Shigella dysenteriae
Globotriaosylceramide
Intestine
Diarrhea, hemorrhagic colitis, hemo-
lytic uremic syndrome
Shiga - like toxin
Escherichia coli
Globotriaosylceramide,
globotetraosylceramide
Intestine
Diarrhea, hemorrhagic colitis, hemo-
lytic uremic syndrome
a
Globotriaosylceramide (p
k
), Gal
α
1,4Gal
β
1,4Glc
β
1,1Cer; globotetraosylceramide, GalNAc
β
1,3Gal
α
1,4Gal
β
1,4Glc
β
1,1Cer; Forssman antigen, GalNAc
α
1,3GalNAc
β
1,3
Gal
α
1,4Gal
β
1,4Glc
β
1,1Cer; GloboA, GalNAc
α
1,3(Fuc
α
1,2)Gal
β
1,3GalNAc
β
1,3Gal
α
1,4Gal
β
1,4Glc
β
1,1Cer;
asialo - GM1,
Gal
β
1,3GalNAc
β
1,4Gal
β
1,4Glc
β
1,1Cer;
asialo - GM2,
GalNAc
β
1,4Gal
β
1,4Glc
β
1,1Cer;
N
- acetyllactosamine,
Gal
β
1,4GlcNAc;
Le
b
,
Fuc
α
1,2Gal
β
1,3(Fuc
α
1,4)GlcNAc; H type 1, Fuc
α
1,2Gal
β
1,3GlcNAc;
ALe
b
, GalNAc
1,4)GlcNAc; SLe
x
, Sia
α
1,3(Fuc
α
1,2)Gal
β
1,3(Fuc
α
α
2,3Gal
β
1,4(Fuc
α
1,3)GlcNAc; P1, Gal
α
1,4Gal
β
1,4GlcNAc
β
1,3Gal
β
1,4Glc
β
1,1Cer; blood group B
antigen, Gal
α
1,3(Fuc
α
1,2)GlcNAc; Le
a
, Gal
β
1,3(Fuc
α
1,4)GlcNAc; Le
x
, Gal
β
1,4(Fuc
α
1,3)GlcNAc; Le
y
, Fuc
α
1,2Gal
β
1,4(Fuc
α
1,3)GlcNAc; GM1, Gal
β
1,3GalNAc
β
1,4
(NeuAc
α
2,3)Gal
β
1,4Glc
β
1,1Cer; GM2, GalNAc
β
1,4(NeuAc
α
2,3)Gal
β
1,4Glc
β
1,1Cer; paragloboside, Gal
β
1,4GlcNAc
β
1,3Gal
β
1,4Glc
β
1,1Cer.
