Biomedical Engineering Reference
In-Depth Information
may kill swiftly in high concentrations, may also have an effect on an organism's
behaviour or its susceptibility to environmental stress over its lifetime, in the case
of low concentration exposure.
Availability also features as an important influence, both in a gross, physical
sense and also in terms of its biological availability to the individual organism,
together with issues of its age and general state of health. Other considerations
also play a significant part in the overall picture of toxicity and we shall return
to look at some of them in greater depth shortly.
Persistence
This is the duration of effect. Environmental persistence is a particularly
important factor in pollution and is often linked to mobility and bioaccumulation.
Highly toxic chemicals which are environmentally unstable and break down
rapidly are less harmful than persistent substances, even though these may be
intrinsically less toxic.
Mobility
The tendency of a pollutant to disperse or dilute is a very important factor in its
overall effect, since this affects concentration. Some pollutants are not readily
mobile and tend to remain in 'hot-spots' near to their point of origin. Others
spread readily and can cause widespread contamination, though often the distri-
bution is not uniform. Whether the pollution is continuous or a single event, and
if it arose from a single point or multiple sources, form important considerations.
Ease of control
Many factors contribute to the overall ease with which any given example of pol-
lution can be controlled, including the mobility of the pollutant, the nature, extent
or duration of the pollution event and local site-specific considerations. Clearly,
control at source is the most effective method, since it removes the problem at its
origin. However, this is not always possible and in such cases, containment may
be the solution, though this can itself lead to the formation of highly concen-
trated hot-spots. For some substances, the dilute and disperse approach, which
is discussed more fully later in this chapter, may be more appropriate, though
the persistence of the polluting substances must obviously be taken into account
when making this decision.
Bioaccumulation
As is widely appreciated, some pollutants, even when present in very small
amounts within the environment, can be taken up by living organisms and become
concentrated in their tissues over time. This tendency of some chemicals to be
taken up and then concentrated by living organisms is a major consideration,
since even relatively low background levels of contamination may accumulate
up the food chain.
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