Biomedical Engineering Reference
In-Depth Information
repeat pattern
Name
Topology,
comments
Sequence
Reference
Coiled coil
K LEALEGK LEALEGK LEALEGK LEALEGK LEALEG
g abcdefg abcdefg abcdefg abcdefg abcdef
Hodges [36]
Coil-Ser
Ac- E WEALEKK LAALESK LQALEKK LEALEHG -NH
2
DeGrado [64]
TRI
triple helix
G LKALEEK LKALEEK LKALEEK LKALEEK G
Pecoraro (1998)
CoilV
a
L
d
E VEALEKK VAALESK VQALEKK VEALEHG
DeGrado
CoilV
a
L
d
V16C
E VEALEKK VAALESK CQALEKK VEALEHG
Pecoraro
a
1
A
Ac-GKLEELLKKLLEELKG-OH
DeGrado [80]
a
1
B
Ac-GELEELLKKLKELLKG-OH
DeGrado
GCN4-p1
GCN4 Leu-zipper
motif
R MKQLEDK VEELLSK NYHLENE VARLKKL VGER
g abcdefg abcdefg abcdefg abcdefg abcdef
DeGrado, Eisenberg
5-helix bundle
1
Ac-ELLEKL- HCys(SR)-K- HCys(SR)-LEELLKK-NH
2
, R: Acm,
SCH
3
,H
Chmielewski [88]
a
2
B
helix-loop-helix
Ac-GELEELLKKLKELLK-GPRRG-ELEELLKKLKELLKG-
NH
2
DeGrado
a
2
C
helix-loop-helix
Ac-GEVEELLKKFKELWK-GPRRG-EIEELFKKFKELIKG-
NH
2
DeGrado
a
2
D
helix-loop-helix
Ac-GEVEELEKKFKELWK-GPRRG-EIEELHKKFHELIKG-
NH
2
DeGrado
1
by formation of five disulfide bridges
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