Biomedical Engineering Reference
In-Depth Information
Fig. 4.2. Two-dimensional
geometrical
description:
heart
domain
Ω
H ,
torso
domain
Ω
T
(extramyocardial regions), heart-torso interface
Σ
and torso external boundary
Γ
ext
The resulting coupled system can be formulated in terms of V m , u e , w and the
torso potential u T as follows (see, e.g., [53, 61]):
t w + g ( V m , w )= 0 , in Ω H × ( 0 , T ) ,
χ m t V m + I ion ( V m , w ) div ( σ i V m ) div ( σ i u e )= I app in Ω H × ( 0 , T ) ,
div ( σ i + σ e ) u e div ( σ i V m )= 0 nΩ H × ( 0 , T ) ,
div ( σ T u T )= 0 nΩ T × ( 0 , T ) ,
(4.8)
σ T
u T ·
n T =
0 n
Γ ext × (
0
,
T
) ,
σ i V m · n + σ i u e · n = 0 nΣ × ( 0 , T ) ,
u T = u e
on
Σ × ( 0 , T ) ,
σ e u e · n = σ T u T · n T
on
Σ × ( 0 , T ) ,
V m , w
w 0 . The boundary condition on
with the initial conditions V m
|
=
|
=
t
=
0
t
=
0
def
= ∂Ω
Γ
\ Σ
states that no current can flow from the external torso surface (see
ext
T
Fig. 4.2).
The coupled system of Eqs. (4.8) is often known in the literature as the full bido-
main or coupled bidomain model (see, e.g., [14, 61]). It can be considered as the
“gold standard” in the modelling of the ECG (see, e.g., [38, 53, 61]).
Remark 2. A common approach to reduce the computational complexity of (4.8)
consists of uncoupling the computation of
from that of u T , by neglecting
the electrical torso-to-heart feedback (see, e.g., [14, 38, 50]). Thus, the coupling
conditions (4.7) are replaced by
(
w
,
V m ,
u e )
u T =
u e
on
Σ ,
(4.9)
σ e
u e ·
n
=
0 n
Σ ,
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