Biomedical Engineering Reference
In-Depth Information
Fig. 8.14. Building a composite coupled electrophysiology-calcium-mechanics cell model from
three separately developed cell models (see text)
Fig. 8.15. The sequence of steps used in evaluating clinical indices or designing a treatment strat-
egy by fitting models to patient images and then computing physiological function using biophys-
ically based models. Illustrations here are for cardiac images and models from the euHeart project
(www.euheart.eu), but the workflow is equally applicable to all organ systems
mented (using an image processing toolkit) and fitted with generic finite element
models from a virtual population database (stored in a PACS system). The patient's
anatomically-specific model is then combined with pre-existing models (from the
model repository) and solved subject to patient-specific boundary conditions (e.g.
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