Biomedical Engineering Reference
In-Depth Information
Fig. 1.3.
Compliance-induced mismatch in the timing of inlet vs. outlet flow rates (left) measured
simultaneously from a life-sized silicone-based aneurysm model (right). Adapted from [20]
adults, we noted a small but significant mean delay of 13 msec between ICA and
ECA peak flow rates [23], despite the fact that these were measured from the same
MRI slice location. This observation was consistent with an earlier MRI-based study
by Marshall et al. [24], which showed what appeared to be a
50 msec delay for
younger adults. This may be explained by the fact that the ICA, usually having thin-
∼
Fig. 1.4.
Two options for reconciling measured flow rate waveforms with a rigid CFD model. Left:
Starting point is a set of typical normal carotid artery inlet (CCA) and outlet (ICA, ECA) waveforms,
exhibiting a 50 msec delay due to the more compliant ICA. Top right: First option aligns the ICA
waveform. Bottom right: Second option maintains the ICA delay, but then overestimates ECA flow
dynamics to maintain instantaneous mass conservation
