The Effects of Photodynamic Therapy in Oral Biofilms - Antibiofilm Agents: From Diagnosis to Treatment and Prevention - page 451

disintegration of the biofilm microbial community to control the growth of micro-
organisms in the oral cavity. Thus, PDT may be an alternative to conventional
periodontal therapeutic methods. Although PDT is still in the experimental stage of
development and testing, the method can be an adjunct to conventional antibacterial
measures in periodontology in places of difficult access for mechanical treatment
(Malik et al. 2010 ). PDT is a safe, minimally invasive and non-toxic treatment to
control biofilm formation (Lee et al. 2012 ; Soukos and Goodson 2011 ).
It is indeed hoped that this therapy will be applied for future clinical use in
dentistry. The success of PDT depends on the choice of the most appropriate dose of
the photosensitiser and the optimal administration time of the photosensitiser after
light activation.
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