Chemistry Reference
In-Depth Information
N
(ICl
2
)
-
NH
+
Cl
I
Cl
I
Cl
I
Cl
CH
3
I
C
C
CH
3
Fig.
8
.56
Addition of halides to
alkenes.
The first reported polystyrene-supported
organogermanium hydrides are obtained by func-
tionalisation of a polystyrene or by polymerisation
of a functionalised styrene; the ease of reduction of
organic halides follows the order: C-I > C-Br > C-Cl
[172] (Fig. 8.59).
polystyrene-triphenylphosphine-halogen complex;
chlorhydrins, bromhydrins and iodhyhydrins are
obtained cleanly [173].
3.16 Isoxazolidines
Hydroxylamines, when oxidised by perruthenate-
exchanged resins [102], give nitrones that are
trapped by dipolarophiles such as acrylates in a one-
pot reaction to give isoxazolidines.
3.15 Halohydrins
The opening of steroidal epoxides into sensitive halo-
hydrins is performed in neutral conditions with the
