Biomedical Engineering Reference
In-Depth Information
TABLE 7.1
(Continued )
ee (%)
(Configuration)
Catalyst (mol%)
Conditions
Yield (%)
Reference
OMe
50% KOH aq, Toluene, 0
C
95
96 (
R
)
20
Ar
MeO
Br
-
+
MeO
MeO
Bu
Bu
N
MeO
Ar
OMe
(
S
)-15
(0.01 mol%) (Ar = 3,4,5-F
3
-C
6
H
2
)
OMe
15M KOH aq, Toluene, 0
C
89
97 (
R
)
21
t
-Bu
Ar
Br
-
+
N
H
t
-Bu
Ar
OMe
16
(1 mol%) (Ar = 3,5-(CF
3
)
2
-C
6
H
3
)
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