Biology Reference
In-Depth Information
Budding yeast
?
Histones
GCGAAAANNGAAC
Polo
CDK
Hcm1p
HCM
NDD1
MBF
S
G2
Fkh2p
RNR1
MCB
Mcm1p
CDK
Fkh
CDC5
SBF
CLN1
SCB
M
G1
Yox1p
Mcm1p
ECB
CLN3
Ace2p
Swi5p
SIC1
SWI5/ACE2
CDK
Fission yeast
Asm2p
AACCCT
Histones
MBF
cdc22
+
MCB
Ace2p
S
eng1
+
ACE2
G1
Polo
PBF
plo1
+
PCB
M
G2
?
spd1
+
Novel 3
Figure 2.4. Integration of cell cycle control proteins with cell cycle regulated gene expression in
budding and fission yeasts. For each yeast species, a single gene is shown to represent the
group of genes that are transcribed at particular cell cycle times. Where known the name
or DNA sequence of the upstream activating sequence, and the transcription factor are
indicated. Related transcription factor complexes in the two yeasts are shown by the
same color. For details of each, see text.
through directly binding to and phosphorylating the transcription factors that
regulate them (Anderson
et al.
, 2002; Darieva
et al.
, 2006; Fu
et al.
, 2008;
Papadopoulou
et al.
, 2008).
