Biology Reference
In-Depth Information
Table 2.1. Cell Cycle Control Mechanisms in Budding and Fission Yeasts
Budding yeast
Fission yeast
Cell cycle
phase
Transcription fac-
tor complex
Transcription
factor complex
UAS name
UAS DNA motif
Components
UAS DNA motif
Components
G1-S
SCB
CNCGAAA
SBF
Swi4p, Swi6p
Not present
Not present
Not present
G1-S
MCB
ACGCGT
MBF (DSC1)
Mbp1p, Swi6p
ACGCGT
MBF (DSC1)
Cdc10p, Res1p,
Res2p, Rep1p,
Rep2p
S
Not named
(histones)
GCGAAAANNGAAC Not characterized
Not characterized
AACCCT
Asm2p
Asm2p
S
HCM
TAAACAA
Hcm1p
Hcm1p
Not characterized
Not characterized Not characterized
G2-M
SFF/FKH
TTNCCNAANNNGG
þ GTAAACAA
SFF
Mcm1p, Fkh1p,
Fkh2p, Ndd1p
Not present
Not present
Not present
G2-M
New 3
Not present
Not present
Not present
ACCNCGCT
Not characterized Not characterized
M-G1
PCB
Not present
Not present
Not present
GNAACN
þ GTAAACAA
PBF
Mbx1p, Fkh2p,
Sep1p
M-G1
ECB
TTNCCNAANNNGG
þ NAATTA
EBF
Mcm1p, Yox1p,
Yhp1p
Not characterized
Not characterized Not characterized
M-G1
SWI5/ACE2
ACCAGCN
Swi5p-Ace2p
Swi5p-Ace2p
CCAGCC
Ace2p
Ace2p
Abbreviated names for transcription factor complexes, UAS (upstream activating sequence) DNA motifs, and constituent proteins. For details of each, see text.
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