Biology Reference
In-Depth Information
A
Cellule
SU
H
R
F
P HR
TM
TM
Virus
6HB
B
II
II
I
I
III
III
III
C
I
IV
III
IV
II
III
II
III
I
III
IV
PF
IV
Figure 4.2. Possible fusion models have evolved for class I (A), class II (B), and class III (C) fusion
proteins from their pre- to postfusion conformations. Ambiguities remain regarding
certain events in membrane fusion promoted by a viral fusion protein. Despite the
diversity in the structure of the fusion proteins, the major steps of the fusion process
are similar. The first step, after EnvGP activation upon receptor binding or acidification
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