Cerebral Malaria: Protection by Erythropoietin - Tissue-Protective Cytokines: Methods and Protocols - page 310

Fig. 3 BIENVENU score showing clinical ranking of infected mice without treatment (Control), infected mice
treated with Epo (Epo), infected mice treated with artesunate (Artesunate), and infected mice treated with
artesunate and Epo (Artesunate Epo). Stage 0 = white; stage 1 = yellow; stage 2 = green; stage 4 = light blue;
death = dark blue

4 Notes

1. Epo has a poor bioavailability as demonstrated in recent
studies: when rhuEpo is administrated at low dose used to pro-
mote erythropoiesis (400 IU/kg), no increase of cerebrospinal
fluid (CSF) Epo concentration is observed. At doses ranging