Neurobiological View of Plants and Their Body Plan - Communication in Plants: Neuronal Aspects of Plant Life - page 24

2.4
Auxin as a Plant Neurotransmitter
Auxin is the most important morphogenic agent shaping the whole plant
body in accordance with two physical parameters - light and gravity (Friml
2003; Sachs 2004). Recently, we proposed that auxin represents a plant-
specific neurotransmitter which is transported, in a light- and gravity-
dependent manner, along the anterior-posterior axis of the plant body
(Baluška et al. 2003a, b, 2004b, 2005a; Barlow et al. 2004). Importantly in
this respect, auxin induces the formation of both vascular strands (plant
nerves) as well as new root apices harbouring the command centre of
the plant body (Baluška et al. 2004b). Root apices represent the major
sink for polar auxin transport, and they also show extreme sensitivity to
externally applied auxin (Jiang and Feldman 2002, 2005). Moreover, lateral
root formation is induced by external auxin: initiation of root primordia is
an endogenous process that recapitulates early embryogenesis (Jiang and
Feldman 2002). In contrast, new shoots and leaves are formed exogenously
from superficial cells.
2.5
Cellular End-Poles as Plant Synapses
Plant synapses are stable actin-supported adhesive domains, assembled at
cellular end-poles (cross-walls) between adjacent plant cells of the same cell
file, across which auxin and other chemical signals are transported from
cell to cell via F-actin-driven and brefeldin A-sensitive vesicular trafficking
pathways (Baluška et al. 2003a, b, 2004b, 2005a; Barlow et al. 2004). Besides
theseconstitutiveplantsynapses,plantsarealsocapableofformingfac-
ultative cell-to-cell junctions with cells of other organisms (plants, fungi,
bacteria). These correspond to 'immunological synapses' (Baluška et al.
2005) - specialized cell-to-cell adhesion domains that involve the plasma
membranes of the two organisms that are opposing each other. Such adhe-
sive domains are also sites of active cell-to-cell transport of molecules and
metabolites. Auxin-transporting plant synapses have been observed only
in root apices where they are responsible for ordering of cells into very reg-
ular cell files (Baluška et al. 1997, 2000, 2003a, b, 2005a; see also Fig. 2.1a).
In contrast, shoot apex cells do not align into such regular files (Fig. 2.1b)
andresembleratheranatomicallyaberrantrootapicesofdiversemutants
(Baluška et al. 2001a, 2003b) or after exposure of growing root apices to
F-actin drugs such as latrunculin B (Baluška et al. 2001b).