Amino Acid Transport in Plants and Transport of Neurotransmitters in Animals: a CommonMechanism? - Communication in Plants: Neuronal Aspects of Plant Life - page 161

Fig. 11.2. Phylogenetic tree of the AA-polyamine-choline ( APC ) superfamily (SLC7) ( Hs
Homo sapiens , At Arabidopsis thaliana ). Maximum parsimony analyses were performed
using PAUP 4.0b10 (Swofford 1998). Heuristic tree searches were executed using 100 ran-
dom sequence additions and the tree bisection-reconnection branch-swapping algorithm
with random sequence analysis. The complete alignment was based on 691 sites; 586 were
phylogenetically informative. Bootstrap values (%) are indicated at branch nodes
1995; Frommer et al. 1993; Hsu et al. 1993; Kwart et al. 1993; Rentsch et al.
1996). AAP mediate H + -coupled uptake of a wide spectrum of AA when
expressed in oocytes (Fischer et al. 2002). At AAP1-5 represent low-affinity
transporters with low selectivity towards AA side chains; only AAP3 and
AAP5 transport basic AA efficiently. AAP6 has an approximately tenfold
higher affinity towards all substrates when compared with other AAP. For
glutamine, glutamate and asparagine, major transport forms of organic