Stereospecific and Stereoselective Suzuki–Miyaura Cross-Coupling Reactions - New Trends in Cross-Coupling: Theory and Applications - page 546

proceeds via the in situ generation of a reactive benzylic iodide
(Scheme 11.17). These reaction conditions are exceptionally interesting for
the development of the Suzuki-Miyaura cross-coupling of alkyl iodides,
especially if they can be generalized outside the class of benzylic

substrates.

11.4 Conclusion
The field of stereospecific and stereoconvergent Suzuki-Miyaura coupling
reactions has developed into a powerful method for several important
classes of substrates. In the years to come, then, the challenge will be to
expand this scope. Considering that, since its development, the Suzuki-
Miyaura reaction has revolutionized the manner in which sp 2 -sp 2 C-C
bonds are prepared, and the further development of this reaction to include
reactions in which stereochemistry is generated or preserved will un-
doubtedly have a huge impact on organic synthesis.

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