Nucleobases, Nucleosides and Nucleotides - Free-Radical-Induced DNA Damage and Its Repair - page 230

Table 10.10. γ -Radiolysis of N 2 O-saturated aqueous solutions of Thy. Products and their G
values (unit: 10 −7 mol J −1 ). A Infante et al. (1973), B Nishimoto et al. (1983a)

Product A B

5,6-Dihydro-5,6-dihydroxythymine (Tg; cis and trans ) 2.4 0.35

5-Hydroxy-5,6-dihydrothymine - 0.09

6-Hydroxy-5,6-dihydrothymine 0.15 0.1

5,6-Dihydrothymine 0.1 0.2

5-Hydroxymethyluacil 0.25 0.3

5-Hydroxy-5-methylbarbituric acid 0.11 -

5-Methylbarbituric acid - 0.06

Formylpyruvylurea 0.12 -

Dimers 0.27 n.d.

Unknown 0.11 -

Thy consumption 4.05 2.8

n.d., Not determined

Table 10.11. -Radiolysis of N 2 O-saturated aqueous solutions of Cyt. Products and their G

values. (Dizdaroglu and Simic 1984b)

γ

G/10 −7 mol J −1 Product

Dimers 3.3

5-Hydroxycytosine 1.5

5,6-Dihydroxycytosine 0.2

5,6-Dihydro-5,6-dihydroxyuracil (Ug) 0.15

6-Hydroxycytosine 0.08

5,6-Dihydro-5,6-dihydroxycytosine (Cg) 0.05

Ura 0.02

Cy t consumption 5. 8