Peroxyl Radicals - Free-Radical-Induced DNA Damage and Its Repair - page 170

Thus, O 2 • − and HO 2 • radicals behave very differently. While the HO 2 • radical
undergoes an H-abstraction [reactions (80)−(83)] and behaves like an ordinary
peroxyl radical, the O 2 • − reaction sequence is initiated by an addition reaction
[reaction (84), see below]. The H-abstraction reaction (80) is slow ( k = 120 dm 3
mol − 1 s − 1 ). Similar conclusions, revising an earlier report (Schulte-Frohlinde et al.
1986), have been obtained by Hildenbrand and Schulte-Frohlinde (1997) for the
reaction of DNA peroxyl radicals with GSH.