Endocrine-Disrupting Pesticides - Pesticides: Evaluation of Environmental Pollution - page 623

They can either bind to the hormone's receptor or mimic the hormone, or they can block
the action of the hormone. Secondly, they can stimulate or inhibit the enzymes respon-
sible for the synthesis or clearance of a hormone and thereby give rise to an increased or
decreased action of the hormone.
Numerous studies have documented the endocrine actions of DDT and its metabolites
in vertebrates (Guillette et al. 2006; see Table 20.2 ). DDT has been taken as an example for
the wide variety of effects of a pesticide.
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