Host response - Orthopaedic Biomaterials in Research and Practice - page 350

Table 14.2 implant site tumors in humans

Time of diagnosis
(years postimplantation) Author and year Device Tumor a

Fracture fixation devices
McDougall (1956) Plate-screws (F 55?) EW (?) 30

Delgado et al. (1958) Plate-screws (F 55?) OS 3

Dube et al. (1972) Plate-screws (F 55?) HE 30

Tayton (1980) Plate-screws (F 75?) EW 6

MacDonald (1981) IM rod (F 75) L 17

Dodison et al. (1983) Plate-screws (F 75) L 7

Ward et al. (1987) Smith-Petersen (F 55) OS 9

Total joint replacement
Bagó-Granell et al. (1984)

Charnley-Mueller THR
(F 75?/UHMWPE)

MFH 2

Swann (1984) b McKee-Farrar THR

(F 75?/F 75?)

MFH 3.3

Penman et al. (1984) Ring THR (F 75/F 75) OS 5.25

Weber (1986) Variable axis TKR (F 75/

UHMWPE)

ES c 3.7

Ryu et al. (1987) Mittlemeier THR (F 75/

Al 2 O 3 )

STS 1.25

Bauer et al. (1987) Charnley-Mueller THR

(F 75/UHMWPE)

OS d 10

Albert et al. (2009) Insall Burstein TKA

(CoCrMo)

AS 10

Iglesias et al. (1994) ? TKA (CoCrMo) MFH 10

Lucas et al. (2001) Long-stem THA (?) MFH 2

Lucas et al. (2001) Osteonics Omnifit

(CoCrMo)

MFH 8

Mallick et al. (2009) Burch Schneider

reinforcement cage
(Ti, broken)

AS 30 (original THA), 10

(revision)

Sources: Bagó-Granell, J. et al., J Bone Joint Surg 66B:38-40, 1984. Bauer, T.W. et al., Trans Soc Biomater
10:36, 1987. Delgado, E.R., Clin Orthop Rel Res 12:315-318, 1958. Dodion, P. et al.,
Histopathology 6:807-813, 1983. Dube, V.E., Fischer, D.E., Cancer 30:1260-1266, 1972.
McDonald, I., Cancer 48:1009-1011, 1980. McDougall, A., J Bone Joint Surg 38B:709-713,
1956. Penman, H.G., Ring, P.A., J Bone Joint Surg 66B:632-634, 1984. Ryu, R.K.N. et al., Clin
Orthop Rel Res 216:207-212, 1987. Swann, M., J Bone Joint Surg 66B:629-631, 1984. Tayton,
K.J.J., Cancer 45:413-415, 1980. Ward, J.J. et al., Trans Soc Biomater 10:106, 1987. Weber, P.C.,
J Bone Joint Surg 68B:824-826, 1986. Iglesias, M.E. et al., J Dermatol Surg Oncol 20:848-849,
1994. Albert, A. et al., Acta Orthop Belg 75:549-553, 2009. Lucas, D.R. et al., Histopathology
39:620-628, 2001. Mallick, A. et al., J Arthroplasty 24: 323e17-323e20, 2009.

a

Tumor types: AS, angiosarcoma; ES, epithelioid sarcoma; EW, Ewing's sarcoma; HE, hemangioendothe-
lioma; L, lymphoma; MFH, malignant fibrous histiocytoma; OS, osteosarcoma; STS, soft tissue sarcoma.

b

Anecdotal reports of three additional cases, including one metastatic osteosarcoma.

c

Previous histiocytoma.

d

Previous enchondroma.